The main bioactive compound in ginger, 6-gingerol, counteracts some of the mechanisms that fuel the autoimmune disease lupus, and its associated condition antiphospholipid syndrome.

Oxidative stress (excessive free radicals and inadequate antioxidants to neutralize them) links gum disease to kidney disease. A 10% increase in gum inflammation increases kidney failure risk by 32%.

In a study of over 52,000, those with brown fat were less likely to develop heart or metabolic-related conditions, including heart disease, heart failure, hypertension, and type 2 diabetes.

Cells that line blood vessels generate fat cells called fibro-inflammatory progenitors that promote inflammation, while the signaling molecule ZFP423 ameliorates this fat-related inflammation in mice.