The Essential Nutrient Choline—a Methyl Donor and Key to Neuronal Health

Quercetin is a flavonoid compound that is well-known for supporting healthy immune system functioning, but recent research has also uncovered links to aspects of healthy aging and longevity. As one of the most commonly consumed free-radical scavengers in the American diet, quercetin is a flavonoid compound found in many common fruits and vegetables, like apples, parsley, citrus, onions, and berries. However, the amounts found in foods (15-50mg) are not always clinically relevant doses and are much lower than you can find in supplements (500-1,000mg). Some longevity-related areas that quercetin has been found to be involved with include clearing senescent cells,...

Fisetin is a flavonoid polyphenol found in many fruits and vegetables, including strawberries, apples, persimmons, cucumbers, and onions—and increasing evidence for its use against cellular senescence is emerging. Senescence is a hallmark of aging, characterized by irreversible growth arrest of cells. Cellular senescence occurs with increasing age or in response to various stressors, including a buildup of reactive oxygen species or ROS—unstable compounds that cause oxidative stress and can damage cells and DNA.  This cellular growth arrest is accompanied by SASP—senescence-associated secretory phenotype—which is a complex mechanism that triggers the secretion of damaging compounds, including proteins, cytokines, and growth factors....

Recent study takes a deep dive in the relationship between magnesium and the hallmarks of aging