Compounded Sermorelin

Medical Prescription

Sermorelin

Semaglutide

Injection • Available only in the USA • SKU: RX005
Title

A Superior Approach to GH Restoration

•  A self-administered peptide injection designed to support healthy aging. 

•  Naturally boosts growth hormone (GH)—at a fraction of the cost of GH therapy. 

Key Ingredient

Sermorelin: 200 mcg to 400 mcg per dose.
Title

First Month Price

$300 $210.00

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Title

Same day prescription approval

Compounded by US-licensed pharmacy

Delivered directly to your home

How it Works

Sermorelin is a peptide that enhances the body's natural growth hormone (GH) production through two key mechanisms:1-3

• Mimics GHRH: Acts like growth hormone-releasing hormone (GHRH), promoting balanced hormone signaling.

• Activates the Pituitary Gland: Binds to GHRH receptors in the anterior pituitary, stimulating GH release in harmony with the body's natural rhythms. 

Health Benefits

Healthy Aging Support

Helps counter age-related GH decline, supporting overall vitality and wellness.4,5

Optimized Body Composition

Encourages lean muscle mass and fat reduction, supporting a strong, healthy physique.5-9

Improved Bone Density

Supports bone mineralization, helping to strengthen the skeletal system.5,10-13

Enhanced Muscle Performance

Improves muscle strength, accelerates post-workout recovery, and helps reduce downtime between training sessions.1,14-17

Anti-Aging Benefits

Declining Hormones

Aging is not just about the passing of time—it’s about how well our body renews itself. GH plays a crucial role in this process, yet levels naturally decline as we age, leading to fatigue, muscle loss, and both visible and invisible signs of aging.  

Optimized Aging

Sermorelin taps into your body's innate regenerative intelligence, naturally awakening GH production and elevating levels to restore youthful energy, support longevity, and enhance overall well-being—without the risks or high costs of GH therapy.  

Key Longevity Pathways Influenced by Growth Hormone Restoration

Growth hormone restoration promotes healthy aging by influencing critical biological pathways, such as stimulating IGF-1 (a growth factor that supports tissue repair and regeneration), enhancing mitochondrial function (which is essential for cellular energy production), and regulating the synthesis of collagen and elastin (key to skin elasticity and joint health). By addressing fundamental hallmarks of aging, growth hormone restoration offers transformative potential for extending healthy lifespan.

Cognition and brain health17-21 

Sleep quality22-24 

Libido and sexual health6,25

Skin quality5,6

Immune resilience26,27

Cardiovascular function28-30

Quality of life6,31

Key Longevity Pathways Influenced by Growth Hormone Restoration

Growth hormone restoration promotes healthy aging by influencing critical biological pathways, such as stimulating IGF-1 (a growth factor that supports tissue repair and regeneration), enhancing mitochondrial function (which is essential for cellular energy production), and regulating the synthesis of collagen and elastin (key to skin elasticity and joint health). By addressing fundamental hallmarks of aging, growth hormone restoration offers transformative potential for extending healthy lifespan.

Reducing oxidative stress and inflammation

Enhancing cellular repair through autophagy

Protecting against cellular senescence

Boosting mitochondrial function

Improving skin hydration and wrinkles

Strengthening bones and joints

Enhancing cognitive function and neuroprotection

Promoting cardiovascular health

Why Choose ProHealth Longevity

Same-day prescription approval 

No insurance required

Compounded by a
US-licensed pharmacy

Lab tested for quality and safety

In stock, ready to ship

Home Delivery with 2-Day Expedited Shipping

Reach Your Weight Goals in 4 Simple Steps

Health Questionnaire

Fill out a quick online health history form. This will take about 5 minutes.

Doctor Review

A licensed medical professional will review your form to confirm eligibility.

Expedited Shipping

Once approved, prescriptions will be shipped from a US-licensed, FDA-regulated pharmacy.

At-Home Support

Receive 24/7 access to our care team for personalized guidance at every step.

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Frequently Asked Questions

Frequently Asked Questions

Frequently Asked Questions

Who should use Sermorelin Injections?

Your healthcare provider will provide detailed instructions. In general, the recommended dose is 0.1–0.2 mL (10–20 units) administered subcutaneously 5–7 days per week.

Why is Sermorelin safer than growth hormone therapy?

Sermorelin is often viewed as a safer alternative to growth hormone (GH) therapy because it naturally stimulates the body's own growth hormone production rather than supplying synthetic GH. This approach maintains natural regulation and promotes balanced, pulsed GH release. By supporting GH production without overriding the body's feedback mechanisms, sermorelin offers a safer, more physiological alternative to synthetic GH therapy.  

Who is a good candidate for Sermorelin?

Sermorelin may be suitable for adults experiencing symptoms of low growth hormone levels, such as decreased muscle mass, fatigue, weight gain, or reduced vitality. It's important to consult with a healthcare provider to determine if Sermorelin is right for you based on your individual health needs.

Avoid use if you have a known allergy to Sermorelin or any of its components, are pregnant or breastfeeding, or have active cancer. 
Use exactly as directed.

Use caution if you have an underactive thyroid (hypothyroidism), as this condition may reduce Sermorelin’s effectiveness. 

How long does it take to receive my medication?

Once your doctor’s approval is secured—typically within 4 hours on weekdays or 12 hours on weekends—your order will ship via two-day expedited delivery.

Are there any side effects?

The most common side effects of Sermorelin include injection site reactions (pain, swelling, redness), headache, flushing, dizziness, and nausea. These are usually mild and transient.

Serious side effects are rare but may include severe allergic reactions, changes in blood pressure, or increased intracranial pressure. Seek immediate medical attention if these occur. 

These are not all the possible side effects of Sermorelin. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Can Sermorelin interact with other medications?

Yes, Sermorelin can interact with glucocorticoids, thyroid hormones, and other medications that affect growth hormone levels. Always inform your healthcare provider of all medications you are taking. 

How long will I need to use Sermorelin?

The duration of use can vary based on individual goals and health needs. Our healthcare provider will recommend a treatment plan and duration that aligns with your specific health objectives.

What is the best way to discontinue Sermorelin?

Consult your healthcare provider: Always seek medical guidance before stopping Sermorelin to ensure a safe and personalized approach.

Gradual tapering: Reduce the dosage gradually (e.g., by 25% per week) to help the body adjust and minimize withdrawal effects. 

Monitor for symptoms: Watch for fatigue, muscle weakness, or mood changes, and contact your doctor if severe symptoms arise.

Support your body: Maintain a healthy diet, regular exercise, and quality sleep, and consider supplements if recommended by your provider. 

*Please note that the product packaging may differ from the image shown. 

References

References

1Ishida J et al. JCSM Rapid Commun. 2020;3(1):3-15. 
2Sigalos JT et al. Sex Med Rev. 2018;6(1):45-53. 
3Granata R et al. Nat Rev Endocrinol. 2025;21(3):196.  
4Corpas E et al. J Clin Endocrinol Metab. 1992;75(2):530-535. 
5Garcia JM et al. Nat Rev Endocrinol. 2025;21(3):180-195. 
6Khorram O et al. J Clin Endocrinol Metab. 1997;82(5):1472-1479.  
7Vitiello MV et al. Dialogues Clin Neurosci. 2001;3(3):229-36.  
8Rudman D et al. N Engl J Med. 1990;323(1):1-6. 
9Papadakis MA et al. Ann Intern Med. 1996;124(8):708-716. 
10Svensson J et al. Endocrine. 2001;14(1):63-66. 
11Merriam GR et al. J Anti-Aging Med. 2004;4(4):221-231. 
12Wydra A et al. Reumatologia. 2023;61(4):239-247. 
13Varlamov E et al. Curr Opin Endocr Metab Res. 2018;3:7-20. 
14Tavares AB et al. Int J Endocrinol. 2013;2013:942030. 
15Vittone J et al. Metabolism. 1997;46(1):89-96. 
16Sinha DK et al. Transl Androl Urol. 2020;9(Suppl 2):S149-S159. 

17Vitiello MV et al. Neurobiol Aging. 2006;27:318323. 
18Baker LD et al. Arch Neurol. 2012;69(11):1420-1429. 
19Friedman SD et al. JAMA Neurol. 2013;70(7):883-890. 
20Ashpole NM et al. Exp Gerontol. 2015;68:76-81. 
21Tang S et al. Sci Rep. 2017;7(1):18110. Published 2017 Dec 22. 
21Kerkhofs M et al. Am J Physiol. 1993;264(4 Pt 1):E594-E598. 
23Marshall L et al. J Clin Endocrinol Metab. 1996;81(3):1009-1013. 
24Guldner J et al. Neurobiol Aging. 1997;18(5):491-495. 
25Sinha DK et al. Transl Androl Urol. 2020;9(Suppl 2):S149-S159. 
26Stanley TL et al. Clin Infect Dis. 2021;73(4):621-630. 
27Chang Y et al. Ann Transl Med. 2021;9(5):406. 
28Bagno LL et al. J Am Heart Assoc. 2015;4(4):e001464. 
29Kanashiro-Takeuchi RM et al. Oncotarget. 2015;6(12):9728-9739. 
30Caicedo D et al. Int J Mol Sci. 2018;19(1):290. Published 2018 Jan 18. 
31Walker RF. Clin Interv Aging. 2006;1(4):307-308.