Longevity Articles

How NAD+ Triple Boost Ultra Triples the Effects on Healthy Aging and Longevity

How NAD+ Triple Boost Ultra Triples the Effects on Healthy Aging and Longevity

The molecule NAD+ is critical to life as we know it, but unfortunately, it declines as we age. NAD+ is a coenzyme, meaning it helps other enzymes function properly. Without NAD+, hundreds of life-giving reactions would not be able to take place—from those on the larger scale, like pumping blood through the body, to microscopic actions, like repairing damaged DNA. 

NAD+ Triple Boost Ultra is a powerful, patent-pending formula designed to support cellular energy and longevity by increasing NAD+ levels in three critical ways. Unlike other NAD+ precursor formulas, NAD+ Triple Boost Ultra combines 10 powerful ingredients to enhance NAD+ production, recycling, and circulation. This formulation helps your body create and use energy more effectively, allowing you to feel more youthful with each passing year.

With scientifically-supported ingredients such as nicotinamide riboside (NR), apigenin, quercetin, PQQ, ginseng, B vitamins, and tryptophan, NAD+ Triple Boost Ultra optimizes NAD+ levels from every angle. 

NAD+ and Aging: What’s the Link?

Some of the leading functions of NAD+ include helping our cell’s mitochondrial powerplants turn food into energy, regulating our circadian rhythm, ensuring proper cell function, and maintaining DNA integrity. 

NAD+ is not only required for maintaining life but also for supporting longevity. However, most people experience a drop in NAD+ levels as they age. Some research has found that levels of this crucial coenzyme can drop by as much as 50% between the ages of 40 and 60, with an additional decline upon reaching older age. 

Concurrent with this drop in NAD+ are increases in signs of accelerated aging or physiological decline—the dysfunctional ​​changes that can occur across all organ systems and contribute to the aging phenotype. 

The Anti-Aging Benefits of NAD+ Triple Boost Ultra

NAD+ Triple Boost Ultra is a powerful blend of age-defying ingredients that takes your health to the next level. 

Here’s what you’ll find in the new NAD+ Triple Boost Ultra:

  • Nicotinamide Riboside: Nicotinamide riboside (NR) is a precursor to NAD+, directly contributing to the increase of NAD+ levels within the body through the Salvage Pathway. NR is only two conversion steps away from NAD+, so your body has to do very little work to activate it into this necessary molecule.
  • Apigenin: Apigenin is the bioactive compound in chamomile, thought to increase antioxidant activity and modulate CD38 activity to support healthy aging. Essentially, apigenin protects NAD+ against destruction by the CD38 enzyme. CD38 becomes more active as we age, destroying critical NAD+ that our cells need for metabolic function and repair. By adding apigenin, your NAD+ stores can remain at higher levels for an extended time. 
  • Tryptophan: This is an amino acid that uses the De Novo Synthesis Pathway, a process that then converts tryptophan into biologically useful NAD+. Some researchers believe that supporting cellular NAD+ synthesis in this way can lead to slower aging and fewer age-related issues commonly associated with NAD+ reduction.
  • B-Vitamins: Niacin, also known as vitamin B3, is converted through the Preiss-Handler Pathway to biologically active NAD+. Other B-vitamins, such as methylcobalamin (the biologically active form of vitamin B-12), support healthy methylation, aiding in the production of SAMe, a key methyl donor that participates in methylation reactions throughout the body to promote a more youthful epigenetic profile. This formulation also provides vitamin B2 (riboflavin) and vitamin B6, which are vital for cellular metabolism and cognitive function.
  • Quercetin: A flavonoid compound found in several fruits and vegetables, quercetin has also been found to modulate CD38 activity and support a healthy inflammation response. Quercetin also helps to activate sirtuins—a family of proteins known as “longevity genes” that help with DNA repair—and may aid in the clearing of senescent cells from the body. Senescent cells are known to secrete inflammatory compounds that increase the expression of the CD38 enzyme, reducing NAD+ levels in healthy cells.
  • Panax Notoginseng: Also known as Chinese ginseng, Panax notoginseng is rich in ginsenosides. When combined with NAD+ precursors, ginsenosides have been found to boost NAD+ levels in certain tissues. Ginsenosides also help maintain mitochondrial function and support healthy inflammatory responses. 
  • PQQ: Pyrroloquinoline quinone (PQQ) is a vitamin-like nutrient that acts as a powerful cofactor. PQQ supports healthy cell function and survival by diminishing the oxidative stress caused by damaging free radicals before being restored by glutathione to an active form. In numerous studies, supplements with PQQ have demonstrated the ability to support mitochondrial function and a healthy inflammatory response, which can support cognitive, cardiovascular, and immune system health. 

How Can NAD+ Triple Boost Ultra Support Healthy Aging?

Boosting NAD+ with NAD Triple Boost Ultra presents a new and effective strategy for slowing the natural decline in cellular energy as we age. But it’s not just NAD+ precursors that you’ll find in this supplement—it’s also loaded with healthy aging compounds that target multiple sides of the aging equation. 

The “triple” in NAD+ Triple Boost Ultra comes from the fact that this supplement enhances NAD+ levels through all three of the main NAD+ synthesis pathways: the Preiss-Handler Pathway, the Salvage Pathway, and the De Novo Synthesis Pathway. By utilizing all three of these pathways, you can support NAD+ levels from all angles.

Plus, it contains additional compounds that support healthy aging through the body’s inflammation response, antioxidant defense, sirtuin activity, mitochondrial function, and more. These actions not only help bolster cellular health but also support organ function and biological system integrity, making it an ideal formula for anyone interested in optimized aging.


References:

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Castro-Portuguez R, Sutphin GL. Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan. Experimental Gerontology. 2020;132:110841. doi:10.1016/j.exger.2020.110841

Clement J, Wong M, Poljak A, Sachdev P, Braidy N. The plasma nad+ metabolome is dysregulated in “normal” aging. Rejuvenation Research. 2019;22(2):121-130. doi:10.1089/rej.2018.2077

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Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018;9:1286. doi:10.1038/s41467-018-03421-7

Salehi B, Venditti A, Sharifi-Rad M, et al. The therapeutic potential of apigenin. Int J Mol Sci. 2019;20(6):1305. doi:10.3390/ijms20061305

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