The NMN transporter Slc12a8 is also found in the lateral hypothalamus, which can regulate the sympathetic nervous system and skeletal muscle function, resulting in healthier aging and energy consumption.  

New research shows that combining supplemental NMN with resveratrol or ginsenosides significantly increases NAD+ levels, with each organ or tissue responding differently.

Differences in an astronaut’s bone response and recovery to microgravity are primarily explained by mission duration, and there may be therapeutic potential of NMN for bone regeneration in astronauts.

A summary of clinical studies from 2021 and 2022 show that NMN treatment impacts exercise capacity, sleep, and fatigue, and provide insight into safety and dosing strategies.