NMN was safe and well-tolerated at 250 mg per day for 12 weeks, supporting mobility, lower limb physical performance, and daytime energy levels — especially when taken in the evening.

The Chinese herb corlyin extended replicative lifespan in yeast, mice, and cultured human cells, possibly by ameliorating senescence — a state of cellular replicative and growth arrest linked to aging.

Supplementing with NADH and CoQ10 can help to bolster ATP production, which supports increased energy levels, mood, and mental focus as we age.

Glycine and N-acetylcysteine (GlyNAC) extends mouse lifespan by 24% and improves age-related abnormalities, including oxidative stress, mitochondrial dysfunction, and glutathione shortages.