World Trade Center responders with current PTSD present with premature aging, altered gene activity called transcriptional aging, and accelerated epigenetic biological clocks.

The sirtuin SIRT6 — also known as a "longevity gene" — improves health markers and provides almost a 30% boost in longevity when mice have increased activity of the protein. 

The antioxidant and autophagic abilities of spermidine make this compound a possible contender for protecting and prolonging fertility with advancing maternal age.

Research links elite soccer or handball training to anti-aging mechanisms in immune cells in women, including maintenance of telomere length and mitochondrial health.