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Brain Health
Healthy Aging
Heart Health
Free Nutritional Advisor
Free Nutritional AdvisorPterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health.
- Supports cardiovascular health*
- Promotes brain cell health*
- Activates sirtuins to support healthy aging
- Boosts effectiveness of NMN
Research-Supported Benefits:
Supports Longevity. Pterostilbene activates “longevity genes” known as sirtuins. Research shows that activating sirtuins promotes cellular health and extends lifespan of animals. 1 2 Activating sirtuins aids in DNA repair, promoting cellular stress resistance, regulating autophagy (cellular detoxification) and inflammation. 3
Promotes Heart Health. Research shows that pterostilbene promotes heart health in a variety of ways, one of which is reducing oxidative stress of the heart. 4 Oxidative stress contributes to inflammation and accelerated aging of heart cells. Reducing levels of oxidative stress reduces risk of age-related decline of heart health.
Protects the Aging Brain. Pterostilbene has been shown to reduce neuroinflammation (inflammation of brain cells), reducing oxidative-stress-related damage to brain cells 5. Research shows that neuroinflammation contributes to age-related brain decline symptoms such related to memory and information processing.6
References:
1. Cheng Y, Di S, Fan C, et al. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury. Apoptosis. 2016;21(8):905-916. doi:10.1007/s10495-016-1258-x
2. Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging. BMB Rep. 2019;52(1):24-34. doi:10.5483/BMBRep.2019.52.1.290 doi:10.5483/BMBRep.2019.52.1.290
3. Vazquez BN, Thackray JK, Serrano L. Sirtuins and DNA damage repair: SIRT7 comes to play. Nucleus. 2017;8(2):107-115. doi:10.1080/19491034.2016.1264552
4. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK/Nrf2/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007/s10557-018-6780-3
5. Park B, Lee YJ. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. J Med Food. 2021;24(3):299-309. doi:10.1089/jmf.2020.4766
6. Ahmad MA, Kareem O, Khushtar M, et al. Neuroinflammation: A Potential Risk for Dementia. Int J Mol Sci. 2022;23(2):616. Published 2022 Jan 6. doi:10.3390/ijms23020616
- Pterostilbene has been shown to activate longevity genes known as sirtuins, which play a critical role in regulating cellular aging.
- Sirtuins require NAD+ for fuel, making pterostilbene and NMN a perfect supplement combination to promote longevity.
- By activating sirtuins, pterostilbene supports DNA stability and promotes DNA repair.
- Pterostilbene’s antioxidant effects promote heart and brain health by reducing oxidative stress and inflammation.
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Capsule | ||
| Servings Per Container: 60 | ||
| Amount Per Serving | %DV | |
| Pterostilbene (Trans-pterostilbene) |
250 mg | † |
| † Daily Value not established. | ||
- OTHER INGREDIENTS: Vegetable capsule, rice flour.
-
DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts,
peanuts. - SUGGESTED DAILY USE: Take 1 capsule once or twice daily, with food, preferably in the morning, or as recommended by your healthcare professional.
- CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
- NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN.
Clinical-Supported Dosing. ProHealth Longevity’s Pterostilbene Pro 250 contains 250 mg of pterostilbene per serving, a clinically effective dose to promote longevity.
Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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