The compound ISRIB blocks overactivation of an internal system called the integrated stress response (ISR); ISRIB treatment improved memory scores and neuron function, reducing cognitive decline in mice.

This study describes a novel way to slowly deliver hydrogen sulfide to mice, improving various aspects of Alzheimer’s disease; this could potentially treat cognitive decline if translated to humans.

This study shows NMN’s potential for preservation of the brain’s microcirculation, showing promise for future research into treatment for cerebrovascular events, such as strokes.

This study provides hope that low-dose NMN supplementation could be a non-invasive and low-risk way to increase fertility and support pregnancies with increasing age.