N-Acetyl Cysteine (NAC) helps with detoxification and making antioxidants. Patients with multiple sclerosis who received NAC for 2 mo. had improvements in the cognition and attention areas of the brain.

Aggressively lowering blood pressure to a systolic target of 120 mmHg rather than 140 mmHg may extend life up to 3 years and reduce death rates by 27% for those at high cardiovascular risk.

In aged mice, NMN supplementation improved neurovascular function by promoting sirtuin activation and mediating genes involved in mitochondrial rejuvenation.

Oligodendrocytes are cells that make myelin (the protein that covers and protects neurons) and are required for long-term memory but reduce with age. In mice, restoring the production prevents memory loss.